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Not all of them are associated with a poor prognosis or with mutations in the MET gene [41]

This statement, published in the peer-reviewed Journal of Endocrinology and Metabolism, represents the consensus finding across all six trials and nearly 900 participants

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You may experience some of the following: Severe Fatigue and Weakness Easy bruising or bleeding Bleeding gums Sore tongue Stomach pain Pale skin Chest Pain Weight loss Loss of appetite Diarrhea Constipation Exhaustion Breathing Difficulties Dizziness Fast or irregular heartbeat Pounding or whooshing in your ears Headache Cold hands or feet Pale or yellow skin Chest pain If this deficiency is not addressed and treated, these complications may arise: Tingling or numbness in the fingers and toes Difficulty walking Depression Mood changes Anxiety Memory loss Disorientation Dementia Contact our office today if you believe you may be at risk and/or are experiencing some of the symptoms listed above

However, their impact on skeletal muscle mitochondrial function, particularly under metabolic stress, remains unclear